The space shuttle Endeavour sits on launch pad 39A as work continues on the shuttle's auxiliary power unit at the Kennedy Space Center in Cape Canaveral, Florida May 1, 2011. [Photo/Agencies]

CAPE CANAVERAL, Florida - The high-profile voyage of Endeavour - the next-to-last space shuttle flight led by the husband of wounded Rep. Gabrielle Giffords - is off until at least next Sunday because of a technical problem.

The latest culprit, believed to be a bad fuse box, illustrates just how complex these space machines are and why NASA's goodbye to the 30-year shuttle program may be a long one.

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Commander Mark Kelly and his five crewmates quickly headed back to Houston on Sunday morning, two days after their first launch attempt was foiled.

Giffords wasn't far behind; she was in Houston by midafternoon, ready to resume rehab at the hospital where she's been undergoing treatment since January, after being shot in the head in an assassination attempt. She had arrived in Florida Wednesday to take part in the excitement of the launch countdown and to see her husband blast off. It was not immediately known if she would be back for a second try.

Her presence added to the drama surrounding Endeavour's liftoff. So did that of President Barack Obama and his family. They were disappointed not to see a launch on Friday, but still dropped by for a tour at Kennedy Space Center anyway. Obama hinted he might make a return visit to see the very last shuttle launch this summer.

The tip-off that Endeavour had a problem was the failure of heaters that are crucial for keeping a fuel line from freezing in space. The launch was called off Friday as the astronauts headed to the pad to board the shuttle. NASA has now traced the problem to the switch box.

Over the decades, space shuttles have encountered all sorts of technical problems, from nose to tail, that have held up launches. So have problems with their tanks and booster rockets.

Fuel leaks. Engine shutdowns. Wiring problems. Stuck valves. Burst hoses. Turbine failures. Hail damage, even woodpecker holes in the insulating foam of fuel tanks.

The list goes on - no surprise given the estimated 1 million parts per shuttle and 2.5 million parts when you throw in the giant fuel tank and two boosters.

Discovery sat out launch for four months before making its final mission in February. It was grounded by a cracked fuel tank. Now it's Endeavour's turn to stall.

"It is kind of funny. It's almost like they don't want to give up," launch director Mike Leinbach said Sunday. "But it's just coincidence."

Taking out the suspect switch box in Endeavour's engine compartment and putting in a new one is relatively straightforward, Leinbach said. But two full days of testing will be needed - on multiple systems associated with the box.

The heaters that remained off Friday are crucial for keeping a hydrazine fuel line from freezing in space, which, in turn, could lead to a rupture and even a fire once the shuttle is back in the atmosphere. The hydrazine feeds the devices that provide hydraulic power to move the main engine at liftoff and the brakes and rudder during landing.

Mike Moses, chairman of the mission management team, said next Sunday is the earliest possible launch date. "There's still a whole lot of short-term work that has to be done," he told reporters.

This will be the last voyage into orbit for Endeavour, NASA's youngest shuttle.